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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa3bb59e0e835bed395651c637eaea65a71c2cf24c1991c9b7a44e9747e2c01' 
  AND token = 's1rDY1fZfuFlxCPq0/2xU6XTdXoppsXAr6jBBJ6qHVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}