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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180ec1f82244f32a817319826cbb852919f7a6b539171b9cb360ebf8e2ce241e' 
  AND token = 'y2DLv1lf2UVTGw2d8FqH6sZ+WI7VfBJZjNh177H3+JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}