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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301b8e44eb383ef308abd4d7d4e568c1ef87d31fab276e589c28f515d3fceec4' 
  AND token = 'Dzw87DkEBL8jaiIgXoEtLAEuRXgPt2d9Wh5EUYjBtls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}