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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f050593ee5ece950840bbb0e713c409f4e82e2228acfd84f83864ef0f3383db' 
  AND token = 'CsRAYwkXP3K66pW5F5uTWYvG8RY5a5lHJR0VcPa+pqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}