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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '183ee038804a8bf8adf16dbb97871f126611b0cb76c93ad576b4742b9ee2a6e4' 
  AND token = 'XHgyx34ruzAMxZ6qYBaY+pJ68p0w/AIfZOZOP/rIrXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}