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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a8917f52e0e9fff6e563b43f1d1e64dcdc59562becb32c28da6b4fbe01df196' 
  AND token = 'VIComhQd4tYnANzQnTuiTZL+HO9Al17sALXDUimi5jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}