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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67861b16b38a0f51ee9ab681ddd110e3469f801550f11f16d173e5f40e39b94b' 
  AND token = 'KZI3KZLdlhTUnOkjghFBTIZ/+OzyAkWrY5RTFsJHFk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}