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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489e0ea4bee1277cd6493f3aa3008f38f6444f932542393ca26b246c0c4be679' 
  AND token = 'n01uUOxaj4tKnOO+rJJC8lJ0H3ujuhqKn6wXKadn/zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}