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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e6e0f6b38118d02ae10147fc36576014dcded620107c084ca22fe0c22158ad' 
  AND token = '3734hoN/gdtwh2aPOzThPMD6DFcyf0eqiLi5Z8jCcVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}