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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf3850b2ac50088238fac2418b765904ab056342002e8b72b5a9172f556e22a' 
  AND token = 'lydcwa3cpeLSmTGjs0uZqsbAs5I+GeLqCWAas8fr51c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}