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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cee022a5fa6a451ebdd24e324c3a20afe4d2cb98ee447684e26577c8f7e99f3' 
  AND token = 'o+3rVJ6zxYCxMWW4s0nGE/7Gg/wqKMK6HEm/0GybQFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}