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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6820e2d7c583de55723551f4fbfe68219ab24498428e12f13fa1f507559c0a9' 
  AND token = 'XRQWVASrbzg8GQFMlQaNiayrpAJSGLH0t0L3TzJvo2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}