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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208b9b7e92c8cb4f6961d85886a2d7b46a1ea227da2f19ff852cef0d0357be9a' 
  AND token = 'u+OF1WAHHGdDdd8AUPuEG0RDn1tBMfHwdPI9m5UWj8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}