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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c645e9a863eb03e82a2625142c102cd3c605f0bfcc73097e3b7756a7a493a7db' 
  AND token = 'kuPeedQlUnH+kb2PeIpGDoCQtW8pneyfU1iCC8f4PK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}