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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d67ee1165a264ba84635072003d629fad8074468a5c1f3599f9b65e3a8bec7e' 
  AND token = 'FfmiRm4sOhLjRR+3oa7GSu1TOYcW4nlSgeAEk8Xsriw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}