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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f02773365dbe446b8361fb3a87746110d1fa61ba328210dc41f783b307e6072a' 
  AND token = 'esfqrqE8srVEGagSH/DNA+G2gWVG9G6CcrlMmd23lCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}