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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4210b9f86a84a056b81eec3df7b69598a58d5b1baa1653c8f613daef8c3a00c' 
  AND token = 'LVSz/FNSJyPdIGw0u7inLjNbQBcSQJEM1wGv3QnIErM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}