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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '927cf438fa41007efc427122cf741e05ae1858e745033cccb4db5ce537192ef9' 
  AND token = 'EsYg7IA3d+Q1Xx920gvEbMgx05ZCbkvF/8JuPvbAQmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}