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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9a17d64c0d714fa095d7d81664453ce4927a57488296af0b00679454a6a1f3' 
  AND token = 'F87m/HAaSu6Y+AnXJZx7+WdZcKbSrgkuxxZsNIeXCFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}