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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d57c131fcc64367935b3660f804552202e0d36b1f9a7ceb8de7a3564a92018' 
  AND token = 'oKqZUtek8eBY2j2Cp3wHOxx+lR044/T9MHf9J8djEl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}