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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3650918ea0c66cf667d4c132d0ab7376f327138e107207bb326af80f8702b3' 
  AND token = 'h6Yy4j3yEggBJLgkbAtFRI0+bE3hmiCjMfHjQ2XxNlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}