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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11fa63cf5f1e0dbcaee581be7ec6778e4c10330b204398e5d8a920f6df315fd5' 
  AND token = 'dQgXxr3yvvPn4mrYoLVZ4nsFqcE9WA9coMpyuk/Q58U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}