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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05181c00d4c12da505605eac9c9dc94b8734f243f245436836a64cdb59daca8d' 
  AND token = 'ne2vNurPjAVU0+vmI8MPINy1dqBhrsNyQOiYuUT6BUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}