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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd506d12bcb7b09e1ce70984bfd3d429e0de6317c10186d3ff89de4a638209e32' 
  AND token = 'cPAh67Fe+ua2zRM+WkxXHh7FrQvI+XPMVnuSSnGRSTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}