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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49cdad3055f8a79b52ac4fb28796db976006d1b3be1b1b664b77ea704b7bfae' 
  AND token = 'd111RyNNjy+RwLhhqHh36azJ+btFn9CujfPQOiIPneo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}