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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1a0223479037922a7604671a6d3678e110f008eafa8953ea6a49c24c29d319' 
  AND token = 'zMOBJYcaV5L2qxz0kI7miI7OD8QW+2glQPsykb5r4u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}