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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f245c42e7eec4d628453147d4c8f56c7bad6008a1a03aa76f01fe763e96a38e4' 
  AND token = 'cKsebMR1k8oleCp2rPxo2b7NvnaEp93e/pgDOEdif98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}