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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1981d4dc29fdb2f7a973b4a17fbc9f90a734fcc52948a460accd395ca72d0895' 
  AND token = '+SVZdG3TgLuCBzLAZOsWtETVcb/YE+ps9I/IVU3c1bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}