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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fde53b1b0c7ac8507c5efba89ef79404e4818a5454773e448683bb4891021374' 
  AND token = 'o4xAEsWaqpvU8YS6YyyjDDoFaxZdPC8mFw2u8t8vur0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}