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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b21ca63fd5b684433bb3dee4ea4675d60212995dd2e82709d9333f551044cafd' 
  AND token = 'bRBFXrRCfxrsL06UPWZoA+i2z56+mU3xqTqzyhutz10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}