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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b77602c75d2dd0b67a1736d5ae988a27de24d70ef6f98b55fda7134ffe0f65a0' 
  AND token = 'em2jtt7IVQeoyx4WzBE6XCFwo7nd4J8vGYKXqDaaAuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}