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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c5fb0c57c5835df7c8f324b95b8048d742cf7eba4cc1b63cc8033c6377359d0' 
  AND token = 'bov6kIahsNlbLfKRjgkIE/r+PIC4fbZPumcm17dx0Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}