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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3361ece5d006fa0b4d63826acdf7b9e0e3cb047c9d9437a4b310783c60784402' 
  AND token = '0rrMghWkXRy2Czr207UaQRqXWtjrVMQ+fVrlXaTOOJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}