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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fdf705f6f85b9827dbd6146b22c8553606817889a3eff53f657b8fd18133307' 
  AND token = 'ip69B3xDIWx8eZSG5MOPz6w8+uOfgVJegFWLxwt9x1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}