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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e77aa10c28be4f0228e15b938cc6accb54b8d1c9fe1c9edf60edff93a6d2b397' 
  AND token = 'e1ZUAwsQXttTP9lL67bJH5QsQmbyoRot3kRQdQJhE2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}