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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05803238308573581f1a4322d296ce650f067cd9566cf14590cc98e519128b41' 
  AND token = 'RtJECcgF7gfIyYP9rmXKMys26I7eXNc/VeMvQpHv4Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}