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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e13ea37d0480c8b3e8033f41d047a4e80dff54c6f86cecf4f2227fbd2cff77' 
  AND token = 's5JrpHtKyFuqWgQG/x0szl05r8Xlu0nlt/H3djJDRkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}