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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97e17c05d42591653da8e0416605d8c4e78d41ec494f8d5ddc3cb5afc715880f' 
  AND token = '1gPwZWTsUM7llmpFbc2TXppAYWw1EMxf67jbM3wUwiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}