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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aef0b824934b33ae34f95bcb495fa4677593685e02a206236813f6fa5304de23' 
  AND token = '56B+gTsv/nzUo2o5S5Qj4WWGAb3ZrCZ8KyFUK5XkceY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}