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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b16d8cf87df1f21e3b00baf979516c423aeca7aabf9305dfdfc0ee0b3d361e6f' 
  AND token = 'Pq0fPM14PZTfkgYlkoPoFOyN/TJ+SVy0i+KfBE1m2gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}