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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd7e20107deefb5f58d9315cf2f2f4cbbc05e5ed7f8454cf28566282250f8125' 
  AND token = 'LhnqTdE7/PszSDw5TsxAnUHAcTd4keoUkO14vxtrhv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}