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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d00f9162cb6df04c9af6d38c07b813339177db138112749877b901864baba6' 
  AND token = '6yr68k7klWysI+UF7dm7C+pNJWuZ19+TRPVdhJL99s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}