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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fa14b60fb89943410e1605ad34f3cf32bec854f4fc1dc70fd1bc69c4e1c66d8' 
  AND token = 'IUSMBT1XcwPIkCDZJ2GX8UkVAu4zoANzpdmM282xrCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}