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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec5fe9a30e995dc5966f21b490f65d9c8b487e2bf3da105ed5aab1d69838b068' 
  AND token = 's87iNmnWD0tbd8hgYKKmF9Dkx5a24zaoXt3cb/ZI7rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}