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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001f49262d30aebc1e8aa0c5b861f52c58c8ad3f8815553d9fac1a7c9629e2e9' 
  AND token = 'bsXynTAqEQS4dM3/8rpJA89loVklJk6pCsnfdXUW4KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}