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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37a57ce408e0a0842e9e6c7679a4e880a70eaf04a0c16e3a4f61e9775957a47' 
  AND token = '59bB8FRkdpp6QLIG3zo0qkyIkKytfzNTE8MkwXwx3Jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}