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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0186f4e41f9cef585fe449788e9dd7751f7b09f56cd3e21bac9ce077ef51f7' 
  AND token = 'eKnc3o+S0WudlFCB/BYYp+WeQ3+wiaNIy7UdzqO5Dio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}