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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61373dc7998bf20d2284bb149a842b1c920dc3c3e7c42a5e4eeade2152724ad6' 
  AND token = 'DDquEv1mk8KKkiZ7I9bcJ3LSs/UjzUEgD9SrEMED3Gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}