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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f5b1fa400bc5e60d72987e5926442638f2821ae597cabd50563c3f5fc765a6' 
  AND token = 'fODelqmhxLs8BQUZVPu+8SnIM/vcnnkhcl3d6G1u7Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}