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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '436e441fc45e9c697d7f35e62765b40fb08c1d8537787786460d6e7aad81dc35' 
  AND token = '1Vd1eF+SE/RNhpub1wXw9u/i3xSM61w8/xynTa0sMVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}